Tbio TXNL4B Thioredoxin-like protein 4B

Protein Summary

Description

Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.

Uniprot Accession IDs

• Q9NX01
• D3DWS6

Gene Name

• TXNL4B

Ensembl ID

• ENST00000268483
• ENSP00000268483
• ENSG00000140830
• ENST00000423037
• ENSP00000408130
• ENST00000426362
• ENSP00000392310

Symbol

• DIM2
• DLP
• DLP
• Dim2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.76
disease perturbation	0.74
transcription factor perturbation	0.68
virus perturbation	0.68
tissue sample	0.67

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 324.92   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 64   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 324.92   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0