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Tdark
TMEM160
Transmembrane protein 160

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253047
  • ENSP00000253047
  • ENSG00000130748
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.93
kinase perturbation
0.84
histone modification site profile
0.83
tissue sample
0.63
gene perturbation
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.93   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 11   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.93   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 11   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (79)
1 – 10 of 79
VSIG1
Tbio
Novelty:  0.15442611
p_int:  0.998949083
p_ni:  0.001050917
Data Source:  BioPlex
ASPH
Tbio
Family:  Enzyme
Novelty:  0.00291455
p_int:  0.998861186
p_ni:  0.001138814
Data Source:  BioPlex
PCDH9
Tbio
Novelty:  0.03928208
p_int:  0.996106199
p_ni:  0.003893801
Data Source:  BioPlex
KBTBD7
Tdark
Novelty:  0.4947466
p_int:  0.995816646
p_ni:  0.004183354
Data Source:  BioPlex
TNFSF18
Tbio
Novelty:  0.01423949
p_int:  0.985118775
p_ni:  0.014881225
Data Source:  BioPlex
SCCPDH
Tbio
Family:  Enzyme
Novelty:  0.06603568
p_int:  0.95034805
p_ni:  0.04965195
Score:  0.239
Data Source:  BioPlex,STRINGDB
CD44
Tbio
Novelty:  0.00011321
p_int:  0.935453953
p_ni:  0.064546047
Data Source:  BioPlex
C3AR1
Tchem
Family:  GPCR
Novelty:  0.00527301
p_int:  0.860818478
p_ni:  0.139181521
Data Source:  BioPlex
VWCE
Tbio
Novelty:  0.09328341
p_int:  0.822568326
p_ni:  0.177431674
Data Source:  BioPlex
CD96
Tbio
Novelty:  0.02087722
p_int:  0.790086793
p_ni:  0.209913207
Score:  0.209
Data Source:  BioPlex,STRINGDB
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (31)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
3
3
93.3
body mass index
12
5
17
93
hemoglobin measurement
3
3
3
92.2
leukocyte count
2
2
2
80.6
body height
1
1
1
78.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
3
93.3
body mass index
17
93
hemoglobin measurement
3
92.2
leukocyte count
2
80.6
body height
1
78.1
Find similar targets by:
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 160
VGNC:2224
745884
Mouse
MGI:1916344
69094
Rat
RGD:1564549
292654
Dog
transmembrane protein 160
VGNC:47488
476426
Cow
transmembrane protein 160
VGNC:35985
508953
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 160
Mouse
Rat
Dog
transmembrane protein 160
Cow
transmembrane protein 160
Publication Statistics
PubMed Score 0.93
PubMed score by year
PubTator Score 0.58
PubTator score by year