Tbio ARL8B ADP-ribosylation factor-like protein 8B

Protein Summary

Description

May play a role in lysosome motility (PubMed:16537643, PubMed:25898167). May play a role in chromosome segregation (PubMed:15331635).

Uniprot Accession IDs

• Q9NVJ2
• B4DI85

Gene Name

• ARL8B

Ensembl ID

• ENST00000256496
• ENSP00000256496
• ENSG00000134108
• ENST00000419534
• ENSP00000402996
• ENST00000611208
• ENSP00000479202

Symbol

• ARL10C
• GIE1
• Gie1
• ARL10C

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	1
molecular function	0.96
transcription factor perturbation	0.96
interacting protein	0.91
transcription factor binding site profile	0.91

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.02   (req: < 5)

Gene RIFs: 14   (req: <= 3)

Antibodies: 144   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.02   (req: >= 5)

Gene RIFs: 14   (req: > 3)

Antibodies: 144   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0