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Tbio
SETD4
SET domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332131
  • ENSP00000329189
  • ENSG00000185917
  • ENST00000399207
  • ENSP00000382158
  • ENST00000399208
  • ENSP00000382159
  • ENST00000399212
  • ENSP00000382161
  • ENST00000399215
  • ENSP00000382163

Symbol
  • C21orf18
  • C21orf27
  • C21orf18
  • C21orf27
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.88
kinase perturbation
0.76
tissue sample
0.71
transcription factor
0.68
microRNA
0.66


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SET domain containing 4
VGNC:1124
747065
Macaque
SET domain containing 4
696003
Mouse
MGI:2136890
224440
Rat
RGD:619899
245975
Dog
SET domain containing 4
VGNC:46056
487747
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SET domain containing 4
Macaque
SET domain containing 4
Mouse
Rat
Dog
SET domain containing 4
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NVD3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (94)
1 – 10 of 94
SETD6
Tbio
Family: Epigenetic
Novelty: 0.091198
Score: 0.806
Data Source: STRINGDB
SETD5
Tbio
Family: Epigenetic
Novelty: 0.04311822
Score: 0.773
Data Source: STRINGDB
CBR1
Tchem
Family: Enzyme
Novelty: 0.0062295
Score: 0.707
Data Source: STRINGDB
RPL12
Tbio
Novelty: 0.01176619
Score: 0.703
Data Source: STRINGDB
DYNC1LI1
Tbio
Novelty: 0.02164556
Score: 0.694
Data Source: STRINGDB
KDM7A
Tchem
Family: Epigenetic
Novelty: 0.04113733
Score: 0.69
Data Source: STRINGDB
PCDH9
Tbio
Novelty: 0.03928208
Score: 0.673
Data Source: STRINGDB
EEF1AKMT2
Tbio
Family: Enzyme
Novelty: 0.13586312
Score: 0.67
Data Source: STRINGDB
SLC37A3
Tdark
Family: Transporter
Novelty: 0.21571546
Score: 0.67
Data Source: STRINGDB
PCNX1
Tbio
Novelty: 0.07740343
Score: 0.668
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.48

PubMed score by year
PubTator Score  0.95

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer