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Tdark
ACOXL
Acyl-coenzyme A oxidase-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000340561
  • ENSP00000343717
  • ENSG00000153093
  • ENST00000389811
  • ENSP00000374461
  • ENST00000439055
  • ENSP00000407761
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.97
phenotype
0.8
cell type or tissue
0.79
disease
0.6
protein domain
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.12   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 33   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.12   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 33   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (59)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
2
7
10
99
monocyte count
4
6
7
98.9
eosinophil percentage of leukocytes
2
3
3
97.1
lymphocyte count
2
4
4
96.1
eosinophil count
3
2
3
94.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
10
99
monocyte count
7
98.9
eosinophil percentage of leukocytes
3
97.1
lymphocyte count
4
96.1
eosinophil count
3
94.5
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1921371
74121
Rat
RGD:1306814
296138
Dog
acyl-CoA oxidase like
VGNC:37524
611729
Horse
acyl-CoA oxidase like
VGNC:14996
100064086
Cow
acyl-CoA oxidase like
VGNC:25555
100336467
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
acyl-CoA oxidase like
Horse
acyl-CoA oxidase like
Cow
acyl-CoA oxidase like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NUZ1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Beta-oxidation of pristanoyl-CoA (R-HSA-389887)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Beta-oxidation of pristanoyl-CoA
Reactome
Fatty acid metabolism
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Peroxisomal lipid metabolism
Name
Explore in Pharos
Explore in Source
Beta-oxidation of pristanoyl-CoA
Fatty acid metabolism
Metabolism
Metabolism of lipids
Peroxisomal lipid metabolism
Gene Ontology Terms (8)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (51)
1 – 10 of 51
LYG2
Tbio
Family:  Enzyme
Novelty:  0.12091256
Score:  0.664
Data Source:  STRINGDB
ANAPC1
Tbio
Family:  Enzyme
Novelty:  0.0521845
Score:  0.651
Data Source:  STRINGDB
PDCL3
Tbio
Novelty:  0.05786581
Score:  0.638
Data Source:  STRINGDB
ZC3H6
Tdark
Novelty:  1.0427978
Score:  0.625
Data Source:  STRINGDB
ANKRD23
Tbio
Novelty:  0.02066669
Score:  0.614
Data Source:  STRINGDB
SP140
Tbio
Family:  TF; Epigenetic
Novelty:  0.04734307
Score:  0.569
Data Source:  STRINGDB
ATP1B3
Tclin
Family:  Transporter
Novelty:  0.06773518
Score:  0.566
Data Source:  STRINGDB
HTD2
Tdark
Family:  Enzyme
Novelty:  0.15897211
Score:  0.558
Data Source:  STRINGDB
HSD17B4
Tbio
Novelty:  0.00547499
Score:  0.558
Data Source:  STRINGDB
FBLN7
Tbio
Novelty:  0.03423924
Score:  0.531
Data Source:  STRINGDB
Publication Statistics
PubMed Score  4.12

PubMed score by year
PubTator Score  1.91

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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