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Tbio
SLC39A9
Zinc transporter ZIP9

Protein Summary
Description
May act as a zinc-influx transporter.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000336643
  • ENSP00000336887
  • ENSG00000029364
  • ENST00000555840
  • ENSP00000450639
  • ENST00000556605
  • ENSP00000452385
  • ENST00000557046
  • ENSP00000451833

Symbol
  • ZIP9
  • ZIP9
  • ZIP-9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.91
histone modification site profile
0.81
transcription factor binding site profile
0.76
virus perturbation
0.76
microRNA
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.32   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.32   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (91)
1 – 10 of 91
CD44
Tbio
Novelty:  0.00011321
p_int:  0.99997619
p_ni:  0.00002381
Data Source:  BioPlex
TTI2
Tdark
Novelty:  0.18394695
p_int:  0.999813748
p_ni:  0.000186252
Data Source:  BioPlex
FKRP
Tbio
Novelty:  0.00798137
p_int:  0.999427233
p_ni:  0.000572757
p_wrong:  1e-8
Data Source:  BioPlex
HIP1R
Tbio
Novelty:  0.02502713
p_int:  0.999090415
p_ni:  0.000909585
Data Source:  BioPlex
DNAJC13
Tbio
Novelty:  0.03251995
p_int:  0.999086772
p_ni:  0.000913228
Data Source:  BioPlex
TPST2
Tbio
Family:  Enzyme
Novelty:  0.02551048
p_int:  0.99907765
p_ni:  0.00092231
p_wrong:  4e-8
Data Source:  BioPlex
SLC25A24
Tbio
Family:  Transporter
Novelty:  0.06151955
p_int:  0.998477764
p_ni:  0.001522236
Score:  0.175
Data Source:  BioPlex,STRINGDB
OSTC
Tbio
Family:  Enzyme
Novelty:  0.06699106
p_int:  0.998178083
p_ni:  0.001760272
p_wrong:  0.000061645
Data Source:  BioPlex
HPCAL1
Tbio
Novelty:  0.04434155
p_int:  0.998003165
p_ni:  0.001996561
p_wrong:  2.74e-7
Data Source:  BioPlex
CANT1
Tbio
Family:  Enzyme
Novelty:  0.02640333
p_int:  0.997474841
p_ni:  0.002524794
p_wrong:  3.65e-7
Data Source:  BioPlex
Pathways (3)
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Zinc homeostasis
WikiPathways
Nuclear Receptors Meta-Pathway
WikiPathways
NRF2 pathway
Name
Explore in Pharos
Explore in Source
Zinc homeostasis
Nuclear Receptors Meta-Pathway
NRF2 pathway
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
2
2
89
myeloid white cell count
1
1
1
70.2
neutrophil percentage of leukocytes
1
1
1
68.6
leukocyte count
1
1
1
61.4
lymphocyte percentage of leukocytes
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neutrophil count
2
89
myeloid white cell count
1
70.2
neutrophil percentage of leukocytes
1
68.6
leukocyte count
1
61.4
lymphocyte percentage of leukocytes
1
54.4
Find similar targets by:
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 39 member 9
VGNC:8212
452998
Macaque
solute carrier family 39 member 9
712430
Mouse
MGI:1914820
328133
Rat
RGD:1311236
314275
Dog
solute carrier family 39 member 9
VGNC:46408
610146
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 39 member 9
Macaque
solute carrier family 39 member 9
Mouse
Rat
Dog
solute carrier family 39 member 9
Publication Statistics
PubMed Score 21.32
PubMed score by year
PubTator Score 9.99
PubTator score by year