Tchem KIF15 Kinesin-like protein KIF15

Protein Summary

Description

Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.

Uniprot Accession IDs

• Q9NS87
• Q17RV9
• Q69YL6
• Q96JX7
• Q9H280

Gene Name

• KIF15

Ensembl ID

• ENST00000326047
• ENSP00000324020
• ENSG00000163808
• ENST00000627272
• ENSP00000486004
• ENSG00000280610

Symbol

• KLP2
• KNSL7
• KLP2
• HKLP2
• KNSL7
• NY-BR-62

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.99
histone modification site profile	0.92
transcription factor binding site profile	0.85
transcription factor perturbation	0.8
cellular component	0.72

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kif15

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Microtubule Binding Motor Protein / Kinesin-like Protein Kif15

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.12   (req: < 5)

Gene RIFs: 38   (req: <= 3)

Antibodies: 183   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.12   (req: >= 5)

Gene RIFs: 38   (req: > 3)

Antibodies: 183   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0