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Tbio
GKN1
Gastrokine-1

Protein Summary
Description
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377938
  • ENSP00000367172
  • ENSG00000169605

Symbol
  • AMP18
  • CA11
  • FOV
  • CA11
  • AMP18
  • BRICD1
  • foveolin
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.71
cell line
0.57
cell type or tissue
0.54
disease perturbation
0.49
trait
0.46


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.12   (req: < 5)
Gene RIFs: 33   (req: <= 3)
Antibodies: 299   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.12   (req: >= 5)
Gene RIFs: 33   (req: > 3)
Antibodies: 299   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
gastrokine 1
VGNC:10653
735918
Mouse
MGI:1913533
66283
Rat
RGD:735014
297418
Dog
gastrokine 1
VGNC:41246
612599
Horse
gastrokine 1
VGNC:18364
100061374
Species
Name
OMA
EggNOG
Inparanoid
Chimp
gastrokine 1
Mouse
Rat
Dog
gastrokine 1
Horse
gastrokine 1
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (37)
1 – 10 of 37
LEG1
Tbio
Novelty: 0.04089511
p_int: 0.999550099
p_ni: 0.000006689
p_wrong: 0.000443212
Score: 0.309
Data Source: BioPlex,STRINGDB
LYZL1
Tbio
Family: Enzyme
Novelty: 0.10945096
p_int: 0.998523098
p_ni: 0.00000191
p_wrong: 0.001474992
Data Source: BioPlex
CST1
Tbio
Novelty: 0.02399609
p_int: 0.997277876
p_ni: 0.002664109
p_wrong: 0.000058015
Score: 0.219
Data Source: BioPlex,STRINGDB
AMY1A
Tchem
Family: Enzyme
Novelty: 0.00210045
p_int: 0.990466857
p_ni: 0.009533143
Data Source: BioPlex
PIGR
Tbio
Novelty: 0.0025812
p_int: 0.984056915
p_ni: 0.015941504
p_wrong: 0.000001581
Score: 0.215
Data Source: BioPlex,STRINGDB
CST4
Tbio
Novelty: 0.00773554
p_int: 0.979072309
p_ni: 0.020925382
p_wrong: 0.000002309
Score: 0.239
Data Source: BioPlex,STRINGDB
ZG16B
Tbio
Novelty: 0.08792924
p_int: 0.896206039
p_ni: 0.103793792
p_wrong: 1.69e-7
Data Source: BioPlex
MUC7
Tbio
Novelty: 0.00750654
p_int: 0.876129708
p_ni: 0.000104068
p_wrong: 0.123766224
Score: 0.232
Data Source: BioPlex,STRINGDB
IGHA1
Tbio
p_int: 0.810175741
p_ni: 0.189824259
Data Source: BioPlex
CAPN9
Tbio
Novelty: 0.0431286
Score: 0.901
Data Source: STRINGDB
Publication Statistics
PubMed Score  51.12

PubMed score by year
PubTator Score  35.38

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer