Tbio GPR173 Probable G-protein coupled receptor 173

Protein Summary

Description

Orphan receptor. This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009]

Uniprot Accession IDs

• Q9NS66
• B1B0A5

Gene Name

• GPR173

Ensembl ID

• ENST00000332582
• ENSP00000331600
• ENSG00000184194

Symbol

• SREB3
• SREB3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.64
tissue	0.54
kinase perturbation	0.48
biological process	0.46
cell line	0.43

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Probable G-protein Coupled Receptor 173

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Probable G-protein Coupled Receptor 173

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 200   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 200   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0