Tbio THSD1 Thrombospondin type-1 domain-containing protein 1

Protein Summary

Description

The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009]

Uniprot Accession IDs

• Q9NS62
• A2A3J3
• B2RCF5
• Q6P3U1
• Q6UXZ2

Gene Name

• THSD1

Ensembl ID

• ENST00000258613
• ENSP00000258613
• ENSG00000136114
• ENST00000349258
• ENSP00000340650
• ENST00000648254
• ENSP00000497520

Symbol

• TMTSP
• TMTSP
• UNQ3010

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.83
kinase perturbation	0.71
tissue sample	0.62
PubMedID	0.57
protein complex	0.53

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.85   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 186   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.85   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 186   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0