PNO1
RNA-binding protein PNO1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.93 | ||
kinase perturbation | 0.93 | ||
protein complex | 0.92 | ||
histone modification site profile | 0.9 | ||
transcription factor perturbation | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Reactome | Metabolism of RNA | ||||
Reactome | rRNA modification in the nucleus and cytosol | ||||
Reactome | rRNA processing | ||||
Reactome | rRNA processing in the nucleus and cytosol | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Metabolism of RNA | ||||
rRNA modification in the nucleus and cytosol | ||||
rRNA processing | ||||
rRNA processing in the nucleus and cytosol | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
intelligence | 2 | 3 | 2 | 5.8 | 50.5 | ||||
lifestyle measurement | 1 | 1 | 1 | 37.6 | |||||
Varicose veins | 1 | 1 | 1 | 33 | |||||
potassium measurement | 1 | 1 | 1 | 28.1 | |||||
diastolic blood pressure change measurement | 1 | 1 | 0 | 12 | 26.6 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
intelligence | 2 | 5.8 | 50.5 | ||||
lifestyle measurement | 1 | 37.6 | |||||
Varicose veins | 1 | 33 | |||||
potassium measurement | 1 | 28.1 | |||||
diastolic blood pressure change measurement | 0 | 12 | 26.6 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | partner of NOB1 homolog | VGNC:339 | 100613305 | |||||
Macaque | partner of NOB1 homolog | 100337566 | ||||||
Mouse | MGI:1913499 | 66249 | ||||||
Rat | RGD:727882 | 289809 | ||||||
Dog | partner of NOB1 homolog | VGNC:44749 | 474623 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | partner of NOB1 homolog | |||||
Macaque | partner of NOB1 homolog | |||||
Mouse | ||||||
Rat | ||||||
Dog | partner of NOB1 homolog | |||||
PMID | Year | Title |
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