INPP5E
72 kDa inositol polyphosphate 5-phosphatase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
co-expressed gene | 0.87 | ||
virus perturbation | 0.83 | ||
kinase perturbation | 0.76 | ||
tissue sample | 0.7 | ||
cellular component | 0.62 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ARL13B-mediated ciliary trafficking of INPP5E | ||||
Reactome | Cargo trafficking to the periciliary membrane | ||||
Reactome | Cilium Assembly | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ARL13B-mediated ciliary trafficking of INPP5E | ||||
Cargo trafficking to the periciliary membrane | ||||
Cilium Assembly | ||||
Metabolism | ||||
Metabolism of lipids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
14 | 10 | 4 | 1.1 | 98.8 | |||||
3 | 4 | 1 | 1.2 | 96.3 | |||||
HbA1c measurement | 3 | 3 | 3 | 94.5 | |||||
2 | 2 | 0 | 1.2 | 93.4 | |||||
4 | 4 | 1 | 1.1 | 92.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
4 | 1.1 | 98.8 | |||||
1 | 1.2 | 96.3 | |||||
HbA1c measurement | 3 | 94.5 | |||||
0 | 1.2 | 93.4 | |||||
1 | 1.1 | 92.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | inositol polyphosphate-5-phosphatase E | 748603 | ||||||
Macaque | inositol polyphosphate-5-phosphatase E | 710121 | ||||||
Mouse | MGI:1927753 | 64436 | ||||||
Rat | RGD:620478 | 114089 | ||||||
Dog | inositol polyphosphate-5-phosphatase E | VGNC:42033 | 607443 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | inositol polyphosphate-5-phosphatase E | |||||
Macaque | inositol polyphosphate-5-phosphatase E | |||||
Mouse | ||||||
Rat | ||||||
Dog | inositol polyphosphate-5-phosphatase E | |||||
PMID | Year | Title |
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