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Tbio
CMC2
COX assembly mitochondrial protein 2 homolog

Protein Summary
Description
May be involved in cytochrome c oxidase biogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000219400
  • ENSP00000219400
  • ENSG00000103121
  • ENST00000564249
  • ENSP00000456841
  • ENST00000565650
  • ENSP00000455457
  • ENST00000565914
  • ENSP00000455723

Symbol
  • C16orf61
  • DC13
  • C16orf61
  • 2310061C15Rik
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
transcription factor perturbation
0.94
histone modification site profile
0.78
transcription factor binding site profile
0.76
cell type or tissue
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.9   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.9   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (52)
1 – 10 of 52
CHCHD4
Tbio
Novelty:  0.01204944
Score:  0.945
Data Source:  STRINGDB
ATP5MC1
Tbio
Family:  Enzyme
Novelty:  0.03538978
Score:  0.932
Data Source:  STRINGDB
GFER
Tchem
Family:  Enzyme
Novelty:  0.00338563
Score:  0.92
Data Source:  STRINGDB
TOMM40
Tbio
Novelty:  0.0041507
Score:  0.91
Data Source:  STRINGDB
ACO2
Tbio
Family:  Enzyme
Novelty:  0.00276725
Score:  0.909
Data Source:  STRINGDB
TIMM22
Tbio
Family:  Enzyme
Novelty:  0.12627933
Score:  0.908
Data Source:  STRINGDB
BCS1L
Tbio
Family:  Enzyme
Novelty:  0.01764582
Score:  0.906
Data Source:  STRINGDB
IDH3G
Tbio
Family:  Enzyme
Novelty:  0.04861242
Score:  0.905
Data Source:  STRINGDB
HSPD1
Tbio
Novelty:  0.00018924
Score:  0.903
Data Source:  STRINGDB
HSPA9
Tchem
Novelty:  0.00235171
Score:  0.903
Data Source:  STRINGDB
Pathways (2)
Mitochondrial protein import (R-HSA-1268020)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Mitochondrial protein import
Reactome
Protein localization
Name
Explore in Pharos
Explore in Source
Mitochondrial protein import
Protein localization
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
3
2
3
88.3
glycine measurement
4
2
4
86.7
amino acid measurement
2
2
2
69.6
mean corpuscular hemoglobin concentration
1
1
1
64.9
protein measurement
1
1
1
57.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mosaic loss of chromosome Y measurement
3
88.3
glycine measurement
4
86.7
amino acid measurement
2
69.6
mean corpuscular hemoglobin concentration
1
64.9
protein measurement
1
57.8
Find similar targets by:
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
C-X9-C motif containing 2
VGNC:9003
454264
Macaque
C-X9-C motif containing 2
106995097
Mouse
MGI:1913781
66531
Rat
RGD:2324599
100363376
Dog
COX assembly mitochondrial protein 2 homolog
102155476
Species
Name
OMA
EggNOG
Inparanoid
Chimp
C-X9-C motif containing 2
Macaque
C-X9-C motif containing 2
Mouse
Rat
Dog
COX assembly mitochondrial protein 2 homolog
Publication Statistics
PubMed Score 89.90
PubMed score by year
PubTator Score 37.34
PubTator score by year