You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
METTL5
Methyltransferase-like protein 5

Protein Summary
Description
Probable methyltransferase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260953
  • ENSP00000260953
  • ENSG00000138382
  • ENST00000392640
  • ENSP00000376415
  • ENST00000409965
  • ENSP00000386582

Symbol
  • HSPC133
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.81
virus perturbation
0.72
tissue sample
0.69
transcription factor perturbation
0.68
cell type or tissue
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.88   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.88   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (26)
1 – 10 of 26
NTF3
Tbio
Novelty:  0.00089023
p_int:  0.976928626
p_ni:  1.4e-8
p_wrong:  0.02307136
Data Source:  BioPlex
LTO1
Tbio
Novelty:  0.0597901
Score:  0.599
Data Source:  STRINGDB
IBA57
Tbio
Family:  Enzyme
Novelty:  0.06327415
Score:  0.576
Data Source:  STRINGDB
TRMT112
Tbio
Family:  Enzyme
Novelty:  0.05451623
Score:  0.57
Data Source:  STRINGDB
CCDC82
Tdark
Novelty:  0.48211191
Score:  0.568
Data Source:  STRINGDB
METTL15
Tdark
Family:  Enzyme
Novelty:  0.4575663
Score:  0.56
Data Source:  STRINGDB
YRDC
Tdark
Novelty:  0.01240103
Score:  0.55
Data Source:  STRINGDB
PSMD14
Tchem
Family:  Enzyme
Novelty:  0.01019285
Score:  0.546
Data Source:  STRINGDB
N6AMT1
Tbio
Family:  Enzyme
Novelty:  0.04804276
Score:  0.532
Data Source:  STRINGDB
DPH1
Tbio
Novelty:  0.02296024
Score:  0.522
Data Source:  STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
1
1
46.1
platelet count
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
1
46.1
platelet count
1
31.4
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 5
VGNC:2013
100613773
Macaque
methyltransferase like 5
707119
Mouse
MGI:1922672
75422
Rat
RGD:1566062
502632
Dog
methyltransferase like 5
VGNC:43179
478788
Species
Name
OMA
EggNOG
Inparanoid
Chimp
methyltransferase like 5
Macaque
methyltransferase like 5
Mouse
Rat
Dog
methyltransferase like 5
Publication Statistics
PubMed Score 7.88
PubMed score by year
PubTator Score 2.00
PubTator score by year