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Tbio
PAPOLB
Poly(A) polymerase beta

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.32   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.32   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (91)
1 – 10 of 91
CSTF3
Tbio
Novelty:  0.05260909
Score:  0.99
Data Source:  STRINGDB
CSTF2
Tbio
Novelty:  0.01389909
Score:  0.949
Data Source:  STRINGDB
CPSF2
Tbio
Novelty:  0.0510853
Score:  0.911
Data Source:  STRINGDB
FIP1L1
Tbio
Novelty:  0.00520044
Score:  0.877
Data Source:  STRINGDB
SYMPK
Tbio
Novelty:  0.01773552
Score:  0.876
Data Source:  STRINGDB
CPSF1
Tbio
Novelty:  0.04396897
Score:  0.872
Data Source:  STRINGDB
PAPOLA
Tbio
Family:  Enzyme
Novelty:  0.11047902
Score:  0.803
Data Source:  STRINGDB
PAPOLG
Tbio
Family:  Enzyme
Novelty:  0.02468251
Score:  0.802
Data Source:  STRINGDB
CPSF3
Tchem
Novelty:  0.01880576
Score:  0.791
Data Source:  STRINGDB
PCF11
Tbio
Novelty:  0.01882626
Score:  0.764
Data Source:  STRINGDB
Gene Ontology Terms (7)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
parental longevity
1
1
1
17.8
electrocardiography
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
parental longevity
1
17.8
electrocardiography
1
15.8
Find similar targets by:
Publication Statistics
PubMed Score 17.32
PubMed score by year
PubTator Score 9.83
PubTator score by year