You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SNRK
SNF-related serine/threonine-protein kinase

Protein Summary
Description
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296088
  • ENSP00000296088
  • ENSG00000163788
  • ENST00000429705
  • ENSP00000411375
  • ENST00000454177
  • ENSP00000401246

Symbol
  • KIAA0096
  • SNFRK
  • HSNFRK
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
disease perturbation
0.96
molecular function
0.94
protein domain
0.85
virus perturbation
0.85


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.56   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 142   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.56   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1
16.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
16.2
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Protein-Protein Interactions (26)
1 – 10 of 26
ADAMTS12
Tbio
Family: Enzyme
Novelty: 0.03184816
p_int: 0.999999983
p_ni: 1.5e-8
p_wrong: 2e-9
Score: 0.651
Data Source: BioPlex,STRINGDB
GDF5
Tbio
Novelty: 0.00218118
p_int: 0.999999949
p_ni: 1.1e-8
p_wrong: 3.9e-8
Score: 0.189
Data Source: BioPlex,STRINGDB
ABHD5
Tbio
Family: Enzyme
Novelty: 0.00806614
p_int: 0.989606359
p_ni: 0.005973322
p_wrong: 0.004420319
Score: 0.325
Data Source: BioPlex,STRINGDB
DUSP5
Tbio
Family: Enzyme
Novelty: 0.00197547
Score: 0.763
Data Source: STRINGDB
CAB39
Tbio
Novelty: 0.01592402
Score: 0.744
Data Source: STRINGDB
DUSP2
Tbio
Family: Enzyme
Novelty: 0.03459749
Score: 0.712
Data Source: STRINGDB
SFRP4
Tbio
Novelty: 0.00174428
Score: 0.669
Data Source: STRINGDB
PDP1
Tbio
Family: Enzyme
Novelty: 0.00442352
Score: 0.668
Data Source: STRINGDB
HEY2
Tbio
Family: TF
Novelty: 0.00569776
Score: 0.641
Data Source: STRINGDB
DUSP1
Tchem
Family: Enzyme
Novelty: 0.00097955
Score: 0.577
Data Source: STRINGDB
Publication Statistics
PubMed Score  137.56

PubMed score by year
PubTator Score  10.82

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: