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Tbio
YAE1
Protein YAE1 homolog

Protein Summary
Description
The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed:26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed:26182403).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000223273
  • ENSP00000223273
  • ENSG00000241127
  • ENST00000432096
  • ENSP00000395777

Symbol
  • C7orf36
  • YAE1D1
  • CIAB2
  • GK003
  • YAE1D1
  • C7orf36
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
interacting protein
0.9
tissue sample
0.68
tissue
0.59
hub protein
0.53


Related Tools
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.51   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NRH1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (31)
1 – 10 of 31
LTO1
Tbio
Novelty:  0.0597901
Score:  0.963
Data Source:  STRINGDB
ABCE1
Tbio
Family:  Transporter
Novelty:  0.00529126
Score:  0.804
Data Source:  STRINGDB
ZC3H4
Tbio
Novelty:  0.14897433
Score:  0.659
Data Source:  STRINGDB
DIDO1
Tbio
Family:  Epigenetic
Novelty:  0.0492858
Score:  0.628
Data Source:  STRINGDB
MMS19
Tbio
Novelty:  0.01978769
Score:  0.626
Data Source:  STRINGDB
CIAO3
Tbio
Novelty:  0.00627147
Score:  0.613
Data Source:  STRINGDB
ZNF804A
Tbio
Novelty:  0.00751648
Score:  0.612
Data Source:  STRINGDB
EBLN1
Tdark
Novelty:  0.51666285
Score:  0.586
Data Source:  STRINGDB
KHDC4
Tdark
Novelty:  0.47115316
Score:  0.586
Data Source:  STRINGDB
CIAPIN1
Tbio
Novelty:  0.01359005
Score:  0.578
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.51

PubMed score by year
PubTator Score  2.06

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer