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Tdark
SDR39U1
Epimerase family protein SDR39U1

Protein Summary
Description
Putative NADP-dependent oxidoreductase. This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) superfamily, which includes both classical and extended types. The encoded protein represents an extended type, with similarity to epimerases. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000399395
  • ENSP00000382327
  • ENSG00000100445

Symbol
  • C14orf124
  • HCDI
  • HCDI
  • C14orf124
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.74
histone modification site profile
0.72
transcription factor binding site profile
0.59
tissue sample
0.56
cell type or tissue
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.15   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 85   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.15   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 85   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (27)
1 – 10 of 27
MRPL12
Tbio
Novelty: 0.10646542
p_int: 0.99999789
p_ni: 7.98e-7
p_wrong: 0.000001312
Score: 0.16
Data Source: BioPlex,STRINGDB
BPNT1
Tbio
Family: Enzyme
Novelty: 0.1114547
p_int: 0.99999788
p_ni: 0.000001862
p_wrong: 2.58e-7
Score: 0.191
Data Source: BioPlex,STRINGDB
HSPD1
Tbio
Novelty: 0.00018924
p_int: 0.999941146
p_ni: 0.000001008
p_wrong: 0.000057846
Score: 0.182
Data Source: BioPlex,STRINGDB
HLA-DRA
Tbio
Novelty: 0.0060214
p_int: 0.999575412
p_ni: 0.000004245
p_wrong: 0.000420343
Data Source: BioPlex
STOML1
Tbio
Novelty: 0.05746576
Score: 0.762
Data Source: STRINGDB
NYNRIN
Tdark
Novelty: 0.12231563
Score: 0.746
Data Source: STRINGDB
STXBP6
Tbio
Novelty: 0.13195671
Score: 0.745
Data Source: STRINGDB
GIMAP7
Tbio
Family: Enzyme
Novelty: 0.15758026
Score: 0.719
Data Source: STRINGDB
KHNYN
Tdark
Novelty: 0.34058138
Score: 0.69
Data Source: STRINGDB
RNF17
Tbio
Family: Epigenetic
Novelty: 0.09240471
Score: 0.667
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.15

PubMed score by year
PubTator Score  3.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer