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Tbio
OTOR
Otoraplin

Protein Summary
Description
This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000246081
  • ENSP00000246081
  • ENSG00000125879

Symbol
  • FDP
  • MIAL
  • FDP
  • MIAL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.78
gene perturbation
0.5
cell line
0.46
tissue
0.45
microRNA
0.44


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.73   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 68.73   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (27)
1 – 10 of 27
OTOS
Tdark
Novelty: 0.0661426
Score: 0.648
Data Source: STRINGDB
SNX3
Tbio
Novelty: 0.02703152
Score: 0.612
Data Source: STRINGDB
GABRB1
Tclin
Family: IC
Novelty: 0.02895574
Score: 0.596
Data Source: STRINGDB
SPAG4
Tbio
Novelty: 0.03721621
Score: 0.568
Data Source: STRINGDB
PM20D2
Tdark
Family: Enzyme
Novelty: 0.63491472
Score: 0.537
Data Source: STRINGDB
ATP5PF
Tbio
Family: Enzyme
Novelty: 0.00585408
Score: 0.532
Data Source: STRINGDB
ENPP4
Tbio
Family: Enzyme
Novelty: 0.09897251
Score: 0.513
Data Source: STRINGDB
BHMT
Tchem
Family: Enzyme
Novelty: 0.00453508
Score: 0.487
Data Source: STRINGDB
AK6
Tbio
Family: Kinase
Novelty: 0.173427
Score: 0.483
Data Source: STRINGDB
ADGRG4
Tdark
Family: GPCR
Novelty: 0.39161511
Score: 0.479
Data Source: STRINGDB
Publication Statistics
PubMed Score  68.73

PubMed score by year
PubTator Score  66.91

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer