ACSS2
Acetyl-coenzyme A synthetase, cytoplasmic
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.94 | ||
molecular function | 0.91 | ||
kinase perturbation | 0.84 | ||
transcription factor binding site profile | 0.77 | ||
small molecule perturbation | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Ethanol oxidation | ||||
Reactome | Metabolism | ||||
Reactome | Mitochondrial biogenesis | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Ethanol oxidation | ||||
Metabolism | ||||
Mitochondrial biogenesis | ||||
Organelle biogenesis and maintenance | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred by Curator (IC) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
appendicular lean mass | 3 | 3 | 7 | 97.1 | |||||
suntan | 1 | 2 | 2 | 96 | |||||
glomerular filtration rate | 3 | 2 | 2 | 8.6 | 92.4 | ||||
BMI-adjusted hip circumference | 3 | 4 | 5 | 86.8 | |||||
electrocardiography | 1 | 1 | 41 | 75.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
appendicular lean mass | 7 | 97.1 | |||||
suntan | 2 | 96 | |||||
glomerular filtration rate | 2 | 8.6 | 92.4 | ||||
BMI-adjusted hip circumference | 5 | 86.8 | |||||
electrocardiography | 41 | 75.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | acyl-CoA synthetase short chain family member 2 | VGNC:13827 | 458441 | |||||
Macaque | acyl-CoA synthetase short chain family member 2 | 706703 | ||||||
Mouse | MGI:1890410 | 60525 | ||||||
Rat | RGD:1305489 | 311569 | ||||||
Dog | acyl-CoA synthetase short chain family member 2 | VGNC:37537 | 477205 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | acyl-CoA synthetase short chain family member 2 | |||||
Macaque | acyl-CoA synthetase short chain family member 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | acyl-CoA synthetase short chain family member 2 | |||||
PMID | Year | Title |
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