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Tbio
UTP3
Something about silencing protein 10

Protein Summary
Description
Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254803
  • ENSP00000254803
  • ENSG00000132467

Symbol
  • CRLZ1
  • SAS10
  • CRL1
  • CRLZ1
  • SAS10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.98
disease perturbation
0.96
transcription factor binding site profile
0.94
histone modification site profile
0.89
virus perturbation
0.85


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.62   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.62   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0