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Tbio
ZNF331
Zinc finger protein 331

Protein Summary
Description
May be involved in transcriptional regulation. May play a role in spermatogenesis. This gene encodes a zinc finger protein containing a KRAB (Kruppel-associated box) domain found in transcriptional repressors. This gene may be methylated and silenced in cancer cells. This gene is located within a differentially methylated region (DMR) and shows allele-specific expression in placenta. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253144
  • ENSP00000253144
  • ENSG00000130844
  • ENST00000411977
  • ENSP00000393336
  • ENST00000449416
  • ENSP00000393817
  • ENST00000504493
  • ENSP00000425517
  • ENST00000511154
  • ENSP00000421014
  • ENST00000511593
  • ENSP00000427439
  • ENST00000512387
  • ENSP00000421728
  • ENST00000513999
  • ENSP00000423156
  • ENST00000648122
  • ENSP00000496977
  • ENST00000648236
  • ENSP00000497263
  • ENST00000648397
  • ENSP00000497726
  • ENST00000648511
  • ENSP00000497652
  • ENST00000649326
  • ENSP00000498006

Symbol
  • RITA
  • ZNF361
  • ZNF463
  • RITA
  • ZNF361
  • ZNF463
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.78
transcription factor
0.64
cell type or tissue
0.58
protein domain
0.58
tissue sample
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.38   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 106   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.38   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0