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Tdark
PRDM7
Probable histone-lysine N-methyltransferase PRDM7

Protein Summary
Description
Probable histone methyltransferase. This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000449207
  • ENSP00000396732
  • ENSG00000126856
  • ENST00000643008
  • ENSP00000496449

Symbol
  • PFM4
  • PFM4
  • ZNF910
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.6
protein domain
0.58
tissue
0.54
cell line
0.47
microRNA
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.22   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 53   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.22   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.9
Data Source:  STRINGDB
CAMKMT
Tbio
Family:  Enzyme
Novelty:  0.00382649
Score:  0.703
Data Source:  STRINGDB
PLOD2
Tbio
Family:  Enzyme
Novelty:  0.00403916
Score:  0.65
Data Source:  STRINGDB
PLOD3
Tbio
Family:  Enzyme
Novelty:  0.02211629
Score:  0.65
Data Source:  STRINGDB
PLOD1
Tbio
Family:  Enzyme
Novelty:  0.00905345
Score:  0.65
Data Source:  STRINGDB
RNF212
Tbio
Family:  Enzyme
Novelty:  0.05189831
Score:  0.626
Data Source:  STRINGDB
CENPBD1
Tdark
Novelty:  4.00168984
Score:  0.556
Data Source:  STRINGDB
ZNF783
Tdark
Family:  TF
Novelty:  2.6332053
Score:  0.542
Data Source:  STRINGDB
ZNF419
Tdark
Family:  TF
Novelty:  0.69013025
Score:  0.54
Data Source:  STRINGDB
ZNF773
Tdark
Family:  TF
Novelty:  0.99356549
Score:  0.54
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

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Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Non-traceable Author Statement (NAS)
NTNU_SB
Disease Associations ()
No disease associations found
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
2
7
7
99.6
hair color
6
6
0
2
99.4
2
2
0
1.3
92.4
3
2
0
1.3
89.7
1
1
0
1.4
80.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
7
99.6
hair color
0
2
99.4
0
1.3
92.4
0
1.3
89.7
0
1.4
80.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Cow
PR domain containing 7-like
520584
Species
Name
OMA
EggNOG
Inparanoid
Cow
PR domain containing 7-like
Publication Statistics
PubMed Score 3.22
PubMed score by year
PubTator Score 2.06
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title