PRDM10
PR domain zinc finger protein 10
Protein Summary
May be involved in transcriptional regulation. The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- ENST00000304538
- ENSP00000302669
- ENSG00000170325
- ENST00000358825
- ENSP00000351686
- ENST00000360871
- ENSP00000354118
- ENST00000423662
- ENSP00000398431
- ENST00000526082
- ENSP00000432237
- KIAA1231
- PFM7
- TRIS
- PFM7
- TRIS
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.79 | ||
transcription factor | 0.78 | ||
microRNA | 0.74 | ||
protein domain | 0.73 | ||
transcription factor binding site profile | 0.69 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 45.35 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 209 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 45.35 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 209 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0