LHX9
LIM/homeobox protein Lhx9
Protein Summary
Involved in gonadal development. This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- ENST00000367387
- ENSP00000356357
- ENSG00000143355
- ENST00000367390
- ENSP00000356360
- ENST00000367391
- ENSP00000356361
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.88 | ||
transcription factor | 0.74 | ||
virus perturbation | 0.64 | ||
PubMedID | 0.63 | ||
molecular function | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 40.22 (req: < 5)
Gene RIFs: 5 (req: <= 3)
Antibodies: 87 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 40.22 (req: >= 5)
Gene RIFs: 5 (req: > 3)
Antibodies: 87 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0