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Tdark
NRIP3
Nuclear receptor-interacting protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000309166
  • ENSP00000310205
  • ENSG00000175352

Symbol
  • C11orf14
  • C11orf14
  • NY-SAR-105
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.77
PubMedID
0.63
transcription factor
0.56
microRNA
0.55
cellular component
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.57   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 187   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.57   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 187   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (24)
1 – 10 of 24
DDI2
Tbio
Novelty:  0.09288646
p_int:  0.999981301
p_ni:  0.000018699
Score:  0.345
Data Source:  BioPlex,STRINGDB
DDI1
Tbio
Novelty:  0.02845222
p_int:  0.999971378
p_ni:  0.000028616
p_wrong:  6e-9
Score:  0.455
Data Source:  BioPlex,STRINGDB
PSMG2
Tbio
Novelty:  0.11082503
p_int:  0.999735163
p_ni:  0.000264713
p_wrong:  1.24e-7
Score:  0.203
Data Source:  BioPlex,STRINGDB
ZDHHC2
Tbio
Family:  Enzyme
Novelty:  0.05221728
Score:  0.607
Data Source:  STRINGDB
PSMD4
Tbio
Family:  Enzyme
Novelty:  0.00614538
Score:  0.526
Data Source:  STRINGDB
MYO18B
Tbio
Novelty:  0.0366177
Score:  0.522
Data Source:  STRINGDB
CNTNAP4
Tbio
Novelty:  0.11964567
Score:  0.515
Data Source:  STRINGDB
RAD23A
Tbio
Novelty:  0.01603801
Score:  0.506
Data Source:  STRINGDB
RAD23B
Tbio
Novelty:  0.00672104
Score:  0.506
Data Source:  STRINGDB
B4GALNT1
Tbio
Family:  Enzyme
Novelty:  0.01060447
Score:  0.501
Data Source:  STRINGDB
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
1
3
80.3
alkaline phosphatase measurement
1
1
0
9.9
75.6
BMI-adjusted waist-hip ratio
2
1
2
42.3
hip circumference
1
1
1
21.5
waist-hip ratio
1
1
1
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
80.3
alkaline phosphatase measurement
0
9.9
75.6
BMI-adjusted waist-hip ratio
2
42.3
hip circumference
1
21.5
waist-hip ratio
1
14.2
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
nuclear receptor interacting protein 3
VGNC:3087
748039
Macaque
nuclear receptor interacting protein 3
704753
Mouse
MGI:1925843
78593
Rat
RGD:1304777
361625
Horse
nuclear receptor interacting protein 3
VGNC:20888
100055591
Species
Name
OMA
EggNOG
Inparanoid
Chimp
nuclear receptor interacting protein 3
Macaque
nuclear receptor interacting protein 3
Mouse
Rat
Horse
nuclear receptor interacting protein 3
Publication Statistics
PubMed Score 2.57
PubMed score by year
PubTator Score 1.59
PubTator score by year