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Tbio
GPR108
Protein GPR108

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264080
  • ENSP00000264080
  • ENSG00000125734

Symbol
  • LUSTR2
  • LUSTR2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.9
transcription factor
0.7
cell line
0.61
virus perturbation
0.55
transcription factor perturbation
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.81   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 189   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.81   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
VSIG8
Tdark
Novelty:  1.16023405
p_int:  0.983274897
p_ni:  0.01670557
p_wrong:  0.000019533
Data Source:  BioPlex
GFAP
Tbio
Novelty:  0.00020932
p_int:  0.973757527
p_ni:  0.000798067
p_wrong:  0.025444406
Data Source:  BioPlex
LRRC15
Tbio
Novelty:  0.03701624
p_int:  0.96755479
p_ni:  0.032445078
p_wrong:  1.32e-7
Data Source:  BioPlex
CLPTM1
Tbio
Novelty:  0.06426049
p_int:  0.95181335
p_ni:  0.04818665
Data Source:  BioPlex
SELENBP1
Tbio
Novelty:  0.00758018
p_int:  0.855399073
p_ni:  0.138739499
p_wrong:  0.005861428
Data Source:  BioPlex
IPPK
Tbio
Family:  Enzyme
Novelty:  0.02169701
p_int:  0.775179443
p_ni:  0.000015772
p_wrong:  0.224804785
Score:  0.189
Data Source:  BioPlex,STRINGDB
GPR137
Tbio
Family:  GPCR
Novelty:  0.0878349
Score:  0.662
Data Source:  STRINGDB
GPR137C
Tdark
Novelty:  3.30248948
Score:  0.661
Data Source:  STRINGDB
CAPNS1
Tbio
Novelty:  0.00954566
Score:  0.642
Data Source:  STRINGDB
TTC16
Tdark
Novelty:  14.55737705
Score:  0.596
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
7
3
0
1.4
96.9
tumor necrosis factor ligand superfamily member 14 measurement
1
3
3
96.7
mean platelet volume
3
3
5
96
2
2
0
1.6
94.1
atrophic macular degeneration
2
2
0
1.8
94.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.4
96.9
tumor necrosis factor ligand superfamily member 14 measurement
3
96.7
mean platelet volume
5
96
0
1.6
94.1
atrophic macular degeneration
0
1.8
94.1
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 108
VGNC:6630
741500
Macaque
G protein-coupled receptor 108
703831
Mouse
MGI:1925558
78308
Rat
RGD:735149
316136
Dog
G protein-coupled receptor 108
VGNC:41393
476727
Species
Name
OMA
EggNOG
Inparanoid
Chimp
G protein-coupled receptor 108
Macaque
G protein-coupled receptor 108
Mouse
Rat
Dog
G protein-coupled receptor 108
Publication Statistics
PubMed Score 3.81
PubMed score by year
PubTator Score 0.63
PubTator score by year
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Related Publications
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PMID
Year
Title