NLRC4
NLR family CARD domain-containing protein 4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
biological process | 0.97 | ||
tissue sample | 0.77 | ||
protein domain | 0.58 | ||
PubMedID | 0.58 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Immune System | ||||
Reactome | Inflammasomes | ||||
Reactome | Innate Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Immune System | ||||
Inflammasomes | ||||
Innate Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Traceable Author Statement (TAS) | HGNC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
interleukin 18 measurement | 2 | 2 | 2 | 95.1 | |||||
testosterone measurement | 1 | 2 | 2 | 82.2 | |||||
sex hormone-binding globulin measurement | 4 | 2 | 4 | 74 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 44.2 | |||||
reticulocyte count | 4 | 1 | 4 | 17.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
interleukin 18 measurement | 2 | 95.1 | |||||
testosterone measurement | 2 | 82.2 | |||||
sex hormone-binding globulin measurement | 4 | 74 | |||||
apolipoprotein A 1 measurement | 1 | 44.2 | |||||
reticulocyte count | 4 | 17.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | NLR family CARD domain containing 4 | VGNC:8253 | 459135 | |||||
Macaque | NLR family CARD domain containing 4 | 706378 | ||||||
Mouse | MGI:3036243 | 268973 | ||||||
Rat | RGD:1309831 | 298784 | ||||||
Horse | NLR family CARD domain containing 4 | VGNC:20765 | 100070605 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | NLR family CARD domain containing 4 | |||||
Macaque | NLR family CARD domain containing 4 | |||||
Mouse | ||||||
Rat | ||||||
Horse | NLR family CARD domain containing 4 | |||||
PMID | Year | Title |
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