Tbio TIMMDC1 Complex I assembly factor TIMMDC1, mitochondrial

Protein Summary

Description

Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.

Uniprot Accession IDs

• Q9NPL8
• D3DN81
• Q6IAJ7
• Q6UWU6
• Q9NPR3
• Q9NPS5
• Q9P0Y6

Gene Name

• TIMMDC1

Ensembl ID

• ENST00000494664
• ENSP00000418803
• ENSG00000113845

Symbol

• C3orf1
• C3orf1
• MC1DN31

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.77
tissue sample	0.68
transcription factor binding site profile	0.63
phenotype	0.61
tissue	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.98   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 26   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.98   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0