ISYNA1
Inositol-3-phosphate synthase 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.86 | ||
transcription factor perturbation | 0.8 | ||
kinase perturbation | 0.71 | ||
histone modification site profile | 0.62 | ||
cell type or tissue | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Inositol phosphate metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Synthesis of IP2, IP, and Ins in the cytosol | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Inositol phosphate metabolism | ||||
Metabolism | ||||
Synthesis of IP2, IP, and Ins in the cytosol | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Mutant Phenotype (IMP) | CACAO | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
growth differentiation factor 15 measurement | 4 | 6 | 7 | 99.3 | |||||
mean corpuscular hemoglobin concentration | 2 | 2 | 2 | 89.7 | |||||
neutrophil percentage of leukocytes | 2 | 2 | 2 | 84.2 | |||||
neutrophil count | 3 | 2 | 3 | 83.3 | |||||
body mass index | 4 | 2 | 5 | 79.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
growth differentiation factor 15 measurement | 7 | 99.3 | |||||
mean corpuscular hemoglobin concentration | 2 | 89.7 | |||||
neutrophil percentage of leukocytes | 2 | 84.2 | |||||
neutrophil count | 3 | 83.3 | |||||
body mass index | 5 | 79.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | inositol-3-phosphate synthase 1 | 719487 | ||||||
Mouse | MGI:1919030 | 71780 | ||||||
Rat | RGD:1359423 | 290651 | ||||||
Dog | inositol-3-phosphate synthase 1 | VGNC:42116 | 476667 | |||||
Horse | inositol-3-phosphate synthase 1 | VGNC:19156 | 100069557 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | inositol-3-phosphate synthase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | inositol-3-phosphate synthase 1 | |||||
Horse | inositol-3-phosphate synthase 1 | |||||
PMID | Year | Title |
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