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Tbio
TM9SF3
Transmembrane 9 superfamily member 3

Protein Classes
Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371142
  • ENSP00000360184
  • ENSG00000077147

Symbol
  • SMBP
  • SMBP
  • EP70-P-iso
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
microRNA
0.88
transcription factor binding site profile
0.85
disease perturbation
0.74
histone modification site profile
0.71


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.66   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 77   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.66   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 77   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
1
2
59
lymphocyte percentage of leukocytes
1
1
1
48.5
monocyte percentage of leukocytes
1
1
1
42.3
metastasis measurement
1
1
0
18.6
15.8
disease progression measurement
1
1
0
18.6
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
59
lymphocyte percentage of leukocytes
1
48.5
monocyte percentage of leukocytes
1
42.3
metastasis measurement
0
18.6
15.8
disease progression measurement
0
18.6
15.8
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane 9 superfamily member 3
VGNC:12512
450645
Macaque
transmembrane 9 superfamily member 3
704905
Mouse
MGI:1914262
107358
Rat
RGD:1564625
309475
Dog
transmembrane 9 superfamily member 3
VGNC:47416
612786
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane 9 superfamily member 3
Macaque
transmembrane 9 superfamily member 3
Mouse
Rat
Dog
transmembrane 9 superfamily member 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9HD45-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (40)
1 – 10 of 40
HTR2C
Tclin
Family:  GPCR
Novelty:  0.00074287
p_int:  0.891072171
p_ni:  0.108927829
Score:  0.179
Data Source:  BioPlex,STRINGDB
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
p_int:  0.865181643
p_ni:  0.134818357
Score:  0.189
Data Source:  BioPlex,STRINGDB
TMED7
Tdark
Novelty:  0.31193294
Score:  0.665
Data Source:  STRINGDB
PGAP2
Tbio
Novelty:  0.06145169
Score:  0.653
Data Source:  STRINGDB
TAC1
Tbio
Novelty:  0.00006575
Score:  0.625
Data Source:  STRINGDB
ZFPL1
Tbio
Novelty:  0.1829181
Score:  0.596
Data Source:  STRINGDB
FAF2
Tbio
Novelty:  0.03048598
Score:  0.569
Data Source:  STRINGDB
C12orf49
Tdark
Novelty:  0.56030929
Score:  0.54
Data Source:  STRINGDB
TRMT6
Tbio
Family:  Enzyme
Novelty:  0.06718902
Score:  0.531
Data Source:  STRINGDB
PPP4R3B
Tbio
Family:  Enzyme
Novelty:  0.0185504
Score:  0.525
Data Source:  STRINGDB
Publication Statistics
PubMed Score  21.66

PubMed score by year
PubTator Score  17.13

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer