TNRC6C
Trinucleotide repeat-containing gene 6C protein
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.95 | ||
protein domain | 0.92 | ||
biological process | 0.79 | ||
transcription factor perturbation | 0.68 | ||
pathway | 0.65 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Beta-catenin independent WNT signaling | ||||
Reactome | Ca2+ pathway | ||||
Reactome | Cellular Senescence | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Cellular responses to stress | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Beta-catenin independent WNT signaling | ||||
Ca2+ pathway | ||||
Cellular Senescence | ||||
Cellular responses to external stimuli | ||||
Cellular responses to stress | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
HbA1c measurement | 9 | 17 | 21 | 99.7 | |||||
mean corpuscular volume | 3 | 5 | 5 | 98.4 | |||||
red blood cell distribution width | 4 | 6 | 10 | 98.1 | |||||
reticulocyte measurement | 3 | 5 | 8 | 95 | |||||
mean reticulocyte volume | 1 | 3 | 3 | 94.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
HbA1c measurement | 21 | 99.7 | |||||
mean corpuscular volume | 5 | 98.4 | |||||
red blood cell distribution width | 10 | 98.1 | |||||
reticulocyte measurement | 8 | 95 | |||||
mean reticulocyte volume | 3 | 94.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | trinucleotide repeat containing 6C | VGNC:48949 | 741899 | |||||
Macaque | trinucleotide repeat containing 6C | 714829 | ||||||
Mouse | MGI:2443265 | 217351 | ||||||
Rat | RGD:1310027 | 303774 | ||||||
Dog | trinucleotide repeat containing 6C | VGNC:47700 | 483340 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | trinucleotide repeat containing 6C | |||||
Macaque | trinucleotide repeat containing 6C | |||||
Mouse | ||||||
Rat | ||||||
Dog | trinucleotide repeat containing 6C | |||||
PMID | Year | Title |
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