Tbio ANO8 Anoctamin-8

Protein Summary

Description

Does not exhibit calcium-activated chloride channel (CaCC) activity.

Uniprot Accession IDs

• Q9HCE9
• A6NIJ0

Gene Name

• ANO8

Ensembl ID

• ENST00000159087
• ENSP00000159087
• ENSG00000074855

Symbol

• KIAA1623
• TMEM16H
• TMEM16H
• KIAA1623

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.68
tissue sample	0.64
molecular function	0.63
transcription factor binding site profile	0.6
cell line	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.58   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 18   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.58   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0