SENP2
Sentrin-specific protease 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.96 | ||
transcription factor perturbation | 0.96 | ||
biological process | 0.95 | ||
histone modification site profile | 0.87 | ||
transcription factor binding site profile | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Processing and activation of SUMO | ||||
Reactome | SUMO is proteolytically processed | ||||
Reactome | SUMOylation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of proteins | ||||
Post-translational protein modification | ||||
Processing and activation of SUMO | ||||
SUMO is proteolytically processed | ||||
SUMOylation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 3 | 3 | 2 | 7.1 | 88.6 | ||||
sex hormone-binding globulin measurement | 6 | 2 | 6 | 81.7 | |||||
BMI-adjusted hip circumference | 2 | 3 | 4 | 77.8 | |||||
urate measurement | 2 | 2 | 2 | 40.6 | |||||
electrocardiography | 1 | 1 | 4 | 26.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 2 | 7.1 | 88.6 | ||||
sex hormone-binding globulin measurement | 6 | 81.7 | |||||
BMI-adjusted hip circumference | 4 | 77.8 | |||||
urate measurement | 2 | 40.6 | |||||
electrocardiography | 4 | 26.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | SUMO specific peptidase 2 | VGNC:8851 | 460902 | |||||
Macaque | SUMO1/sentrin/SMT3 specific peptidase 2 | 700717 | ||||||
Mouse | MGI:1923076 | 75826 | ||||||
Rat | RGD:708378 | 78973 | ||||||
Dog | SUMO specific peptidase 2 | VGNC:46006 | 478661 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | SUMO specific peptidase 2 | |||||
Macaque | SUMO1/sentrin/SMT3 specific peptidase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | SUMO specific peptidase 2 | |||||
PMID | Year | Title |
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