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Tbio
GLOD4
Glyoxalase domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000301328
  • ENSP00000301328
  • ENSG00000167699
  • ENST00000301329
  • ENSP00000301329

Symbol
  • C17orf25
  • HC71
  • CGI-150
  • C17orf25
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.92
histone modification site profile
0.91
disease perturbation
0.83
kinase perturbation
0.81
cellular component
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.22   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 99   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.22   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 99   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
1
7
7
93.1
BMI-adjusted hip circumference
1
7
7
92.1
heel bone mineral density
2
2
2
83.4
4
1
0
1.1
76.1
platelet crit
1
1
1
54.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hip circumference
7
93.1
BMI-adjusted hip circumference
7
92.1
heel bone mineral density
2
83.4
0
1.1
76.1
platelet crit
1
54.4
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
glyoxalase domain containing 4
700076
Mouse
MGI:1914451
67201
Rat
RGD:1307010
363644
Horse
glyoxalase domain containing 4
VGNC:49308
100059869
Cow
glyoxalase domain containing 4
VGNC:50005
512334
Species
Name
OMA
EggNOG
Inparanoid
Macaque
glyoxalase domain containing 4
Mouse
Rat
Horse
glyoxalase domain containing 4
Cow
glyoxalase domain containing 4
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q9HC38-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
BHF-UCL
Protein-Protein Interactions (71)
1 – 10 of 71
NANS
Tbio
Family:  Enzyme
Novelty:  0.00718044
Score:  0.87
Data Source:  STRINGDB
WDR82
Tbio
Novelty:  0.04679153
Score:  0.867
Data Source:  STRINGDB
GLRX5
Tbio
Novelty:  0.01166161
Score:  0.837
Data Source:  STRINGDB
PPIL3
Tbio
Family:  Enzyme
Novelty:  0.09773948
Score:  0.834
Data Source:  STRINGDB
CCDC60
Tdark
Novelty:  0.62801145
Score:  0.773
Data Source:  STRINGDB
CATSPERE
Tdark
Novelty:  0.95910237
Score:  0.701
Data Source:  STRINGDB
GLO1
Tchem
Family:  Enzyme
Novelty:  0.00225012
Score:  0.694
Data Source:  STRINGDB
PARK7
Tbio
Family:  Enzyme
Novelty:  0.00104651
Score:  0.676
Data Source:  STRINGDB
LRRC47
Tdark
Novelty:  0.73509239
Score:  0.672
Data Source:  STRINGDB
PRDX2
Tbio
Novelty:  0.00189751
Score:  0.662
Data Source:  STRINGDB
Publication Statistics
PubMed Score  9.22

PubMed score by year
PubTator Score  5.03

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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