MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
small molecule | 1 | ||
molecular function | 0.97 | ||
transcription factor binding site profile | 0.79 | ||
kinase perturbation | 0.76 | ||
microRNA | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | HIF-1 signaling pathway | ||||
KEGG | MAPK signaling pathway | ||||
KEGG | Insulin signaling pathway | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
HIF-1 signaling pathway | ||||
MAPK signaling pathway | ||||
Insulin signaling pathway | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 2 | 2 | 79.3 | |||||
platelet count | 2 | 2 | 2 | 75.4 | |||||
red blood cell distribution width | 2 | 1 | 2 | 71.9 | |||||
body height | 1 | 1 | 1 | 70 | |||||
body mass index | 1 | 1 | 1 | 54.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 2 | 79.3 | |||||
platelet count | 2 | 75.4 | |||||
red blood cell distribution width | 2 | 71.9 | |||||
body height | 1 | 70 | |||||
body mass index | 1 | 54.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | MAP kinase interacting serine/threonine kinase 2 | VGNC:13225 | 455561 | |||||
Macaque | MAP kinase interacting serine/threonine kinase 2 | 721436 | ||||||
Mouse | MGI:894279 | 17347 | ||||||
Rat | RGD:1305728 | 299618 | ||||||
Dog | MAP kinase interacting serine/threonine kinase 2 | VGNC:43251 | 612212 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | MAP kinase interacting serine/threonine kinase 2 | |||||
Macaque | MAP kinase interacting serine/threonine kinase 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | MAP kinase interacting serine/threonine kinase 2 | |||||
PMID | Year | Title |
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