IL21R
Interleukin-21 receptor
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.7 | ||
trait | 0.61 | ||
cell line | 0.57 | ||
microRNA | 0.56 | ||
transcription factor | 0.54 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interleukin-2 family signaling | ||||
Reactome | Interleukin-21 signaling | ||||
Reactome | Signaling by Interleukins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interleukin-2 family signaling | ||||
Interleukin-21 signaling | ||||
Signaling by Interleukins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | MGI | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
eosinophil count | 4 | 4 | 5 | 96.4 | |||||
5 | 8 | 0 | 1.1 | 92.1 | |||||
eosinophil percentage of leukocytes | 2 | 3 | 3 | 91.8 | |||||
childhood onset asthma | 2 | 1 | 0 | 1.1 | 77.9 | ||||
C-reactive protein measurement | 2 | 1 | 2 | 70.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 5 | 96.4 | |||||
0 | 1.1 | 92.1 | |||||
eosinophil percentage of leukocytes | 3 | 91.8 | |||||
childhood onset asthma | 0 | 1.1 | 77.9 | ||||
C-reactive protein measurement | 2 | 70.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | interleukin 21 receptor | 705759 | ||||||
Mouse | MGI:1890475 | 60504 | ||||||
Rat | RGD:1304950 | 308977 | ||||||
Dog | interleukin 21 receptor | VGNC:41968 | 608011 | |||||
Horse | interleukin 21 receptor | VGNC:19017 | 100066814 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | interleukin 21 receptor | |||||
Mouse | ||||||
Rat | ||||||
Dog | interleukin 21 receptor | |||||
Horse | interleukin 21 receptor | |||||
PMID | Year | Title |
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