Protein Classes
Protein Summary
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
- ENST00000305141
- ENSP00000305877
- ENSG00000171596
- GPR66
- FM3
- FM-3
- GPC-R
- GPR66
- NMU1R
- (FM-3)
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
tissue sample | 0.64 | ||
microRNA | 0.61 | ||
protein domain | 0.58 | ||
cell type or tissue | 0.57 | ||
gene perturbation | 0.55 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 116.76 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 194 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 116.76 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 194 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 6
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Active Ligands (6)
1 – 6 of 6
Pathways (10)
Reactome (8)
KEGG (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 8
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | G alpha (q) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | GPCR ligand binding | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling events | ||||
G alpha (q) signalling events | ||||
GPCR downstream signalling | ||||
GPCR ligand binding | ||||
Gene Ontology Terms (16)
Functions (4)
Components (3)
Processes (9)
Items per page:
10
1 – 4 of 4
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Protein-Protein Interactions (357)
1 – 10 of 357
NMU
Novelty: 0.00347523
Score: 0.993
Data Source: Reactome,STRINGDB
NMS
Novelty: 0.03848674
Score: 0.985
Data Source: STRINGDB
GNRHR
Family: GPCR
Novelty: 0.00227536
Score: 0.942
Data Source: STRINGDB
NTS
Novelty: 0.00035891
Score: 0.94
Data Source: STRINGDB
NPS
Novelty: 0.00011983
Score: 0.928
Data Source: STRINGDB
GNAQ
Novelty: 0.00176666
Score: 0.927
Data Source: STRINGDB
POMC
Novelty: 0.00002654
Score: 0.927
Data Source: STRINGDB
TBXA2R
Family: GPCR
Novelty: 0.00629658
Score: 0.926
Data Source: STRINGDB
GAL
Novelty: 0.00057698
Score: 0.925
Data Source: STRINGDB
S1PR4
Family: GPCR
Novelty: 0.01383323
Score: 0.924
Data Source: STRINGDB
Publication Statistics
PubMed Score 116.76
PubMed score by year
PubTator Score 55.6
PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Sequence
MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLI
1-70
FVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLL
70-140
FEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCR
140-210
GPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSR
210-280
YTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSA
280-350
ANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
350-420
QETDPS
420-426
MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS
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