Tchem NMUR1 Neuromedin-U receptor 1

Protein Summary

Description

Receptor for the neuromedin-U and neuromedin-S neuropeptides.

Uniprot Accession IDs

• Q9HB89
• O43664
• Q7LDP6
• Q8NE20
• NMU-R1

Gene Name

• NMUR1

Ensembl ID

• ENST00000305141
• ENSP00000305877
• ENSG00000171596

Symbol

• GPR66
• FM3
• FM-3
• GPC-R
• GPR66
• NMU1R
• (FM-3)

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.64
microRNA	0.61
protein domain	0.58
cell type or tissue	0.57
gene perturbation	0.55

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Neuromedin-u Receptor 1

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Neuromedin U Receptor / Neuromedin-u Receptor 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 282.49   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 194   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 282.49   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 194   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 80

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0