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Tchem
NMUR1
Neuromedin-U receptor 1

Protein Summary
Description
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305141
  • ENSP00000305877
  • ENSG00000171596

Symbol
  • GPR66
  • FM3
  • FM-3
  • GPC-R
  • GPR66
  • NMU1R
  • (FM-3)
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.64
microRNA
0.61
protein domain
0.58
cell type or tissue
0.57
gene perturbation
0.55


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.7   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 194   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.7   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 194   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 6
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neuromedin U receptor 1
VGNC:2714
739217
Mouse
MGI:1341898
14767
Rat
RGD:619867
65276
Dog
neuromedin U receptor 1 [Source:HGNC Symbol;Acc:HGNC:4518]
Horse
neuromedin U receptor 1
VGNC:20786
100064205
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neuromedin U receptor 1
Mouse
Rat
Dog
neuromedin U receptor 1 [Source:HGNC Symbol;Acc:HGNC:4518]
Horse
neuromedin U receptor 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9HB89-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (10)
Class A/1 (Rhodopsin-like receptors) (R-HSA-373076)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Class A/1 (Rhodopsin-like receptors)
Reactome
G alpha (i) signalling events
Reactome
G alpha (q) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Name
Explore in Pharos
Explore in Source
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
G alpha (q) signalling events
GPCR downstream signalling
GPCR ligand binding
Protein-Protein Interactions (357)
1 – 10 of 357
NMU
Tbio
Novelty: 0.00326109
Score: 0.993
Data Source: Reactome,STRINGDB
NMS
Tbio
Novelty: 0.03324369
Score: 0.985
Data Source: STRINGDB
GNRHR
Tclin
Family: GPCR
Novelty: 0.00203671
Score: 0.942
Data Source: STRINGDB
NTS
Tbio
Novelty: 0.00033201
Score: 0.94
Data Source: STRINGDB
NPS
Tbio
Novelty: 0.00692108
Score: 0.928
Data Source: STRINGDB
GNAQ
Tbio
Novelty: 0.0008997
Score: 0.927
Data Source: STRINGDB
POMC
Tbio
Novelty: 0.00002436
Score: 0.927
Data Source: STRINGDB
TBXA2R
Tclin
Family: GPCR
Novelty: 0.00571066
Score: 0.926
Data Source: STRINGDB
GAL
Tbio
Novelty: 0.0005132
Score: 0.925
Data Source: STRINGDB
S1PR4
Tclin
Family: GPCR
Novelty: 0.01523676
Score: 0.924
Data Source: STRINGDB
Publication Statistics
PubMed Score  137.70

PubMed score by year
PubTator Score  55.6

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer