GNB4
Guanine nucleotide-binding protein subunit beta-4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.99 | ||
protein domain | 0.92 | ||
transcription factor perturbation | 0.91 | ||
microRNA | 0.86 | ||
pathway | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ADP signalling through P2Y purinoceptor 1 | ||||
Reactome | ADP signalling through P2Y purinoceptor 12 | ||||
Reactome | Activation of kainate receptors upon glutamate binding | ||||
Reactome | Adrenaline,noradrenaline inhibits insulin secretion | ||||
Reactome | Aquaporin-mediated transport | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ADP signalling through P2Y purinoceptor 1 | ||||
ADP signalling through P2Y purinoceptor 12 | ||||
Activation of kainate receptors upon glutamate binding | ||||
Adrenaline,noradrenaline inhibits insulin secretion | ||||
Aquaporin-mediated transport | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
diastolic blood pressure | 1 | 1 | 1 | 54.4 | |||||
2 | 3 | 0 | 1.1 | 46.8 | |||||
platelet crit | 1 | 1 | 1 | 29 | |||||
heart rate | 1 | 1 | 1 | 17.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
diastolic blood pressure | 1 | 54.4 | |||||
0 | 1.1 | 46.8 | |||||
platelet crit | 1 | 29 | |||||
heart rate | 1 | 17.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | G protein subunit beta 4 | VGNC:8836 | 460862 | |||||
Macaque | G protein subunit beta 4 | 709489 | ||||||
Mouse | MGI:104581 | 14696 | ||||||
Rat | RGD:1359321 | 294962 | ||||||
Dog | G protein subunit beta 4 | VGNC:41315 | 488087 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | G protein subunit beta 4 | |||||
Macaque | G protein subunit beta 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | G protein subunit beta 4 | |||||
PMID | Year | Title |
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