Tbio CAB39L Calcium-binding protein 39-like

Protein Summary

Description

Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).

Uniprot Accession IDs

• Q9H9S4
• Q5TAW6
• Q6WG71
• Q96FG1
• Q9BZ33

Gene Name

• CAB39L

Ensembl ID

• ENST00000347776
• ENSP00000261669
• ENSG00000102547
• ENST00000355854
• ENSP00000348113
• ENST00000409308
• ENSP00000386375
• ENST00000410043
• ENSP00000386328
• ENST00000610540
• ENSP00000479669

Symbol

• MO2L
• MO25-BETA
• bA103J18.3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.9
histone modification site profile	0.82
transcription factor binding site profile	0.77
transcription factor perturbation	0.74
tissue sample	0.72

Protein Classes

PANTHER Classes

Protein / Calcium-binding Protein / Annexin / Calcium-binding Protein 39-like

DTO Classes

Protein / Calcium-binding Protein / Annexin / Calcium-binding Protein 39-like

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.03   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 161   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.03   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0