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Tdark
DBNDD1
Dysbindin domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000002501
  • ENSP00000002501
  • ENSG00000003249
  • ENST00000304733
  • ENSP00000306407
  • ENST00000568838
  • ENSP00000457625
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.77
cell type or tissue
0.72
tissue sample
0.68
histone modification site profile
0.63
small molecule perturbation
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.56   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 21   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.56   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 21   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
2
2
2
96.7
mathematical ability
1
1
1
73.9
cognitive function measurement
1
1
1
45.6
hair color
1
1
0
1.1
7.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
2
96.7
mathematical ability
1
73.9
cognitive function measurement
1
45.6
hair color
0
1.1
7.4
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (69)
1 – 10 of 69
CSNK1A1
Tchem
Family: Kinase
Novelty: 0.00636472
p_int: 0.999955178
p_ni: 0.000044823
Data Source: BioPlex
CSNK1E
Tchem
Family: Kinase
Novelty: 0.00891859
p_int: 0.999835089
p_ni: 0.000164911
Data Source: BioPlex
CSNK1D
Tchem
Family: Kinase
Novelty: 0.00896935
p_int: 0.999811622
p_ni: 0.000188378
Data Source: BioPlex
HDAC3
Tclin
Family: Epigenetic
Novelty: 0.00393172
p_int: 0.815732274
p_ni: 0.184267676
p_wrong: 5e-8
Data Source: BioPlex
NMT2
Tchem
Family: Enzyme
Novelty: 0.04826835
p_int: 0.802925324
p_ni: 0.197074357
p_wrong: 3.19e-7
Data Source: BioPlex
TCF25
Tbio
Novelty: 0.08961823
Score: 0.814
Data Source: STRINGDB
PDCD5
Tbio
Novelty: 0.00941533
Score: 0.71
Data Source: STRINGDB
DEF8
Tdark
Novelty: 0.21146806
Score: 0.661
Data Source: STRINGDB
ACSF3
Tbio
Family: Enzyme
Novelty: 0.04255285
Score: 0.621
Data Source: STRINGDB
OR4K14
Tdark
Family: oGPCR
Novelty: 4.77119228
Score: 0.621
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.56

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer