Tdark ERVMER34-1 Endogenous retroviral envelope protein HEMO

Protein Summary

Description

Endogenous envelope proteins originate from retroviral envelope proteins, which mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.

Uniprot Accession IDs

• Q9H9K5
• B3KTB4
• Q0P5R3
• Q6NWN0

Gene Name

• ERVMER34-1

Ensembl ID

• ENST00000440542
• ENSP00000460255
• ENSG00000226887
• ENST00000443173
• ENSP00000460602

Symbol

• HEMO
• HEMO
• envMER34

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.79
histone modification site profile	0.65
cell type or tissue	0.63
tissue	0.61
cell line	0.44

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.58   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 4   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.58   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0