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Tbio
SYNPO2L
Synaptopodin 2-like protein

Protein Summary
Description
Actin-associated protein that may play a role in modulating actin-based shape.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372873
  • ENSP00000361964
  • ENSG00000166317
  • ENST00000394810
  • ENSP00000378289
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.67
cellular component
0.63
tissue sample
0.61
cell line
0.58
transcription factor
0.51


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.41   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.41   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
5
4
0
1.1
95
electrocardiography
1
1
11
78.1
C-reactive protein measurement
1
1
1
56.8
2
1
0
1.3
48.5
heart failure
1
1
0
1.1
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
95
electrocardiography
11
78.1
C-reactive protein measurement
1
56.8
0
1.3
48.5
heart failure
0
1.1
35
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
synaptopodin 2 like
VGNC:7264
450900
Macaque
synaptopodin 2 like
714736
Mouse
MGI:1916010
68760
Rat
RGD:1565434
305675
Dog
synaptopodin 2 like
VGNC:47036
100855466
Species
Name
OMA
EggNOG
Inparanoid
Chimp
synaptopodin 2 like
Macaque
synaptopodin 2 like
Mouse
Rat
Dog
synaptopodin 2 like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H987-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (13)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (82)
1 – 10 of 82
MYOM2
Tbio
Novelty:  0.00032062
Score:  0.763
Data Source:  STRINGDB
ANKRD1
Tbio
Novelty:  0.0123593
Score:  0.74
Data Source:  STRINGDB
CMYA5
Tbio
Novelty:  0.05675889
Score:  0.724
Data Source:  STRINGDB
MYOZ1
Tbio
Novelty:  0.03497131
Score:  0.678
Data Source:  STRINGDB
CASQ2
Tbio
Novelty:  0.00775794
Score:  0.671
Data Source:  STRINGDB
TRDN
Tbio
Novelty:  0.00501554
Score:  0.667
Data Source:  STRINGDB
LDB3
Tbio
Novelty:  0.01178009
Score:  0.666
Data Source:  STRINGDB
TTN
Tbio
Family:  Kinase
Novelty:  0.00040356
Score:  0.661
Data Source:  STRINGDB
AOPEP
Tbio
Family:  Enzyme
Novelty:  0.03344862
Score:  0.657
Data Source:  STRINGDB
SMPX
Tbio
Novelty:  0.05084864
Score:  0.652
Data Source:  STRINGDB
Publication Statistics
PubMed Score  5.41

PubMed score by year
PubTator Score  1.48

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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