You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
WDR76
WD repeat-containing protein 76

Protein Summary
Description
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263795
  • ENSP00000263795
  • ENSG00000092470

Symbol
  • CDW14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.79
cell line
0.58
small molecule perturbation
0.57
cellular component
0.52
histone modification site profile
0.52


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.14   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 71   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.14   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 71   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 76
VGNC:1578
467669
Macaque
WD repeat domain 76
711191
Mouse
MGI:1926186
241627
Rat
RGD:1309616
311361
Dog
WD repeat domain 76
VGNC:48388
487529
Species
Name
OMA
EggNOG
Inparanoid
Chimp
WD repeat domain 76
Macaque
WD repeat domain 76
Mouse
Rat
Dog
WD repeat domain 76
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H967-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (61)
1 – 10 of 61
GAN
Tbio
Novelty: 0.01069743
p_int: 1
Score: 0.544
Data Source: BioPlex,STRINGDB
CAMK2D
Tchem
Family: Kinase
Novelty: 0.02326864
p_int: 0.999168324
p_ni: 0.000831676
Data Source: BioPlex
IKZF1
Tbio
Family: TF
Novelty: 0.0016117
p_int: 0.994471761
p_ni: 0.005528239
Score: 0.151
Data Source: BioPlex,STRINGDB
IMPDH1
Tclin
Family: Enzyme
Novelty: 0.00758575
p_int: 0.992677137
p_ni: 0.007322862
p_wrong: 1e-9
Data Source: BioPlex
PARP2
Tclin
Family: Enzyme
Novelty: 0.00545618
p_int: 0.992082941
p_ni: 0.007917059
Score: 0.157
Data Source: BioPlex,STRINGDB
SUPT16H
Tbio
Family: Enzyme
Novelty: 0.01026868
p_int: 0.991942468
p_ni: 0.008057532
Score: 0.57
Data Source: BioPlex,STRINGDB
XPC
Tbio
Novelty: 0.00775175
p_int: 0.989450937
p_ni: 0.010549063
Score: 0.743
Data Source: BioPlex,STRINGDB
SSSCA1
Tdark
Novelty: 0.53523038
p_int: 0.987405872
p_ni: 0.012594128
Data Source: BioPlex
LIG3
Tbio
Family: Enzyme
Novelty: 0.00809038
p_int: 0.92430437
p_ni: 0.075639047
p_wrong: 0.000056582
Score: 0.182
Data Source: BioPlex,STRINGDB
SSRP1
Tbio
Family: TF
Novelty: 0.0143993
p_int: 0.899409664
p_ni: 0.100590336
Score: 0.593
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  13.14

PubMed score by year
PubTator Score  5.26

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer