Tbio COQ10B Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

Protein Summary

Description

Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).

Uniprot Accession IDs

• Q9H8M1
• B7Z1Y4

Gene Name

• COQ10B

Ensembl ID

• ENST00000263960
• ENSP00000263960
• ENSG00000115520

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.85
histone modification site profile	0.84
transcription factor perturbation	0.84
kinase perturbation	0.76
virus perturbation	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.01   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 31   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.01   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0