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Tbio
CAAP1
Caspase activity and apoptosis inhibitor 1

Protein Summary
Description
Anti-apoptotic protein that modulates a caspase-10 dependent mitochondrial caspase-3/9 feedback amplification loop.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000333916
  • ENSP00000369431
  • ENSG00000120159
  • ENST00000625311
  • ENSP00000487373

Symbol
  • C9orf82
  • CAAP
  • CAAP
  • C9orf82
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
ligand (protein) perturbation
0.96
histone modification site profile
0.8
transcription factor binding site profile
0.68
cell line
0.64
tissue sample
0.62


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.42   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.42   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0