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Tdark
NIPAL2
NIPA-like protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341166
  • ENSP00000339256
  • ENSG00000104361
  • ENST00000430223
  • ENSP00000407087

Symbol
  • NPAL2
  • NPAL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.84
small molecule perturbation
0.83
transcription factor perturbation
0.74
histone modification site profile
0.66
transcription factor binding site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.29   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (32)
TXNDC16
Tdark
Novelty:  0.25365147
Score:  0.786
Data Source:  STRINGDB
MRPL53
Tdark
Novelty:  1.0076471
Score:  0.74
Data Source:  STRINGDB
HOXD1
Tbio
Family:  TF
Novelty:  0.03468852
Score:  0.705
Data Source:  STRINGDB
KHK
Tchem
Family:  Kinase
Novelty:  0.00514172
Score:  0.691
Data Source:  STRINGDB
CCDC90B
Tdark
Novelty:  0.64520265
Score:  0.675
Data Source:  STRINGDB
XRCC4
Tbio
Novelty:  0.00305644
Score:  0.661
Data Source:  STRINGDB
WDR74
Tbio
Novelty:  0.07119796
Score:  0.653
Data Source:  STRINGDB
MRE11
Tbio
Novelty:  0.01038348
Score:  0.644
Data Source:  STRINGDB
DYNC2LI1
Tbio
Novelty:  0.05087433
Score:  0.62
Data Source:  STRINGDB
PLP1
Tbio
Novelty:  0.00129083
Score:  0.618
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (2)
Miscellaneous transport and binding events (R-HSA-5223345)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Miscellaneous transport and binding events
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Miscellaneous transport and binding events
Transport of small molecules
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
susceptibility to childhood ear infection measurement
1
1
0
1.1
2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
susceptibility to childhood ear infection measurement
0
1.1
2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
NIPA like domain containing 2
703585
Mouse
MGI:1924488
223473
Rat
RGD:1564315
362899
Dog
NIPA like domain containing 2
VGNC:43816
606846
Cow
NIPA like domain containing 2
VGNC:32082
781492
Species
Name
OMA
EggNOG
Inparanoid
Macaque
NIPA like domain containing 2
Mouse
Rat
Dog
NIPA like domain containing 2
Cow
NIPA like domain containing 2
Publication Statistics
PubMed Score 0.29
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title