Tbio ZNF703 Zinc finger protein 703

Protein Summary

Description

Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development.

Uniprot Accession IDs

• Q9H7S9
• Q5XG76

Gene Name

• ZNF703

Ensembl ID

• ENST00000331569
• ENSP00000332325
• ENSG00000183779

Symbol

• ZEPPO1
• ZPO1
• NLZ1
• ZPO1
• ZEPPO1
• ZNF503L

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.93
disease perturbation	0.79
cell type or tissue	0.78
transcription factor binding site profile	0.77
transcription factor perturbation	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.9   (req: < 5)

Gene RIFs: 20   (req: <= 3)

Antibodies: 264   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.9   (req: >= 5)

Gene RIFs: 20   (req: > 3)

Antibodies: 264   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 16

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0