You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SCAF1
Splicing factor, arginine/serine-rich 19

Protein Summary
Description
May function in pre-mRNA splicing.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000360565
  • ENSP00000353769
  • ENSG00000126461

Symbol
  • SFRS19
  • SRA1
  • SRA1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.96
ligand (protein) perturbation
0.83
tissue sample
0.7
transcription factor
0.67
histone modification site profile
0.59


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.88   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 73   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.88   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 73   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (28)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
1
6
6
97
serum albumin measurement
1
4
4
92.1
hemoglobin measurement
3
3
3
91.7
hematocrit
3
2
3
89.4
red blood cell density measurement
1
1
1
80.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood protein measurement
6
97
serum albumin measurement
4
92.1
hemoglobin measurement
3
91.7
hematocrit
3
89.4
red blood cell density measurement
1
80.9
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SR-related CTD associated factor 1
456211
Mouse
MGI:2141980
233208
Rat
RGD:708405
56081
Dog
SR-related CTD associated factor 1
VGNC:45888
484376
Cow
SR-related CTD associated factor 1
VGNC:34313
785072
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SR-related CTD associated factor 1
Mouse
Rat
Dog
SR-related CTD associated factor 1
Cow
SR-related CTD associated factor 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H7N4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (61)
1 – 10 of 61
LARP4B
Tbio
Novelty:  0.11363794
p_int:  0.999914476
p_ni:  0.000085524
Data Source:  BioPlex
CHAC2
Tbio
Family:  Enzyme
Novelty:  0.14706039
p_int:  0.999848643
p_ni:  0.000151356
Data Source:  BioPlex
PNN
Tbio
Novelty:  0.01395394
p_int:  0.999327786
p_ni:  0.000672214
Score:  0.206
Data Source:  BioPlex,STRINGDB
JMJD6
Tchem
Family:  Enzyme
Novelty:  0.00305479
p_int:  0.998578132
p_ni:  0.001421867
Data Source:  BioPlex
U2AF2
Tbio
Novelty:  0.00590935
p_int:  0.996482584
p_ni:  0.003517413
p_wrong:  2e-9
Score:  0.487
Data Source:  BioPlex,STRINGDB
POLR2J
Tbio
Family:  Enzyme
Novelty:  0.02344868
p_int:  0.995987306
p_ni:  0.004012693
Data Source:  BioPlex
SAP18
Tbio
Family:  Enzyme
Novelty:  0.03918373
p_int:  0.992287297
p_ni:  0.007712687
p_wrong:  1.6e-8
Data Source:  BioPlex
SNRNP70
Tbio
Novelty:  0.00116631
p_int:  0.981094226
p_ni:  0.018864081
p_wrong:  0.000041693
Score:  0.269
Data Source:  BioPlex,STRINGDB
RPL14
Tbio
Novelty:  0.01600377
p_int:  0.976252554
p_ni:  0.023747438
p_wrong:  8e-9
Score:  0.214
Data Source:  BioPlex,STRINGDB
RBM4
Tbio
Novelty:  0.02034191
p_int:  0.976161323
p_ni:  0.023838673
p_wrong:  4e-9
Score:  0.169
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  12.88

PubMed score by year
PubTator Score  14.09

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: