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Tbio
ATP13A3
Probable cation-transporting ATPase 13A3

Protein Summary
Description
ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. Other P-type ATPases include ATP7B (MIM 606882) and ATP7A (MIM 300011).[supplied by OMIM, Aug 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000256031
  • ENSP00000256031
  • ENSG00000133657
  • ENST00000439040
  • ENSP00000416508
  • ENST00000645538
  • ENSP00000494471

Symbol
  • AFURS1
  • AFURS1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
molecular function
0.93
protein domain
0.92
microRNA
0.91
virus perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.34   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.34   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (56)
1 – 10 of 56
LGALS8
Tchem
Novelty:  0.00623836
p_int:  0.999815401
p_ni:  0.000184599
Data Source:  BioPlex
CHRNB4
Tclin
Family:  IC
Novelty:  0.01151716
p_int:  0.99906835
p_ni:  0.00093165
Score:  0.281
Data Source:  BioPlex,STRINGDB
YIPF3
Tbio
Novelty:  0.12021667
p_int:  0.998356792
p_ni:  0.001643208
Data Source:  BioPlex
C5AR2
Tbio
Family:  GPCR
Novelty:  0.01193736
p_int:  0.995769299
p_ni:  0.004230701
p_wrong:  1e-9
Data Source:  BioPlex
CCR6
Tchem
Family:  GPCR
Novelty:  0.00257933
p_int:  0.991977372
p_ni:  0.008022603
p_wrong:  2.5e-8
Data Source:  BioPlex
ADGRG5
Tdark
Family:  GPCR
Novelty:  0.26575982
p_int:  0.985085228
p_ni:  0.014914772
Data Source:  BioPlex
LGALS3
Tchem
Novelty:  0.00032754
p_int:  0.978624801
p_ni:  0.021375187
p_wrong:  1.3e-8
Score:  0.2
Data Source:  BioPlex,STRINGDB
LGALS9
Tchem
Novelty:  0.00381766
p_int:  0.959923372
p_ni:  0.040076628
Score:  0.219
Data Source:  BioPlex,STRINGDB
ISLR
Tbio
Novelty:  0.02936208
p_int:  0.939105747
p_ni:  0.060894253
p_wrong:  1e-9
Score:  0.197
Data Source:  BioPlex,STRINGDB
FCER1A
Tbio
Novelty:  0.00362182
p_int:  0.93038575
p_ni:  0.069547464
p_wrong:  0.000066786
Data Source:  BioPlex
Gene Ontology Terms (8)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin-27 measurement
1
1
1
71.5
TNF-related activation-induced cytokine measurement
1
1
1
60.5
mean platelet volume
2
1
2
29
diastolic blood pressure
1
1
1
24.2
basophil count
1
1
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
interleukin-27 measurement
1
71.5
TNF-related activation-induced cytokine measurement
1
60.5
mean platelet volume
2
29
diastolic blood pressure
1
24.2
basophil count
1
15.8
Find similar targets by:
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ATPase 13A3
VGNC:1741
471045
Macaque
ATPase 13A3
707893
Mouse
MGI:2685387
224088
Dog
ATPase 13A3
VGNC:38243
478607
Horse
ATPase 13A3
VGNC:15641
100069072
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ATPase 13A3
Macaque
ATPase 13A3
Mouse
Dog
ATPase 13A3
Horse
ATPase 13A3
Publication Statistics
PubMed Score 8.34
PubMed score by year
PubTator Score 2.34
PubTator score by year